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The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells

The polycomb repressive complex 1 (PRC1), containing the core BMI1 and RING1A/B proteins, mono-ubiquitinylates histone H2A (H2A(ub)) and is associated with silenced developmental genes at facultative heterochromatin. It is, however, assumed that the PRC1 is excluded from constitutive heterochromatin...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Abdouh, Mohamed, Hanna, Roy, El Hajjar, Jida, Flamier, Anthony, Bernier, Gilbert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697155/
https://ncbi.nlm.nih.gov/pubmed/26468281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662403
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