Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer’s disease in old Bmi1+/− mice

Sporadic Alzheimer’s disease (AD) is the most common cause of dementia. However, representative experimental models of AD have remained difficult to produce because of the disease’s uncertain origin. The Polycomb group protein BMI1 regulates chromatin compaction and gene silencing. BMI1 expression i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: El Hajjar, Jida, Chatoo, Wassim, Hanna, Roy, Nkanza, Patrick, Tétreault, Nicolas, Tse, Yiu Chung, Wong, Tak Pan, Abdouh, Mohamed, Bernier, Gilbert
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346086/
https://ncbi.nlm.nih.gov/pubmed/30679733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37444-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars