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Mechanisms for Rescue of Correctable Folding Defects in CFTRΔF508
Premature degradation of CFTRΔF508 causes cystic fibrosis (CF). CFTRΔF508 folding defects are conditional and folding correctors are being developed as CF therapeutics. How the cellular environment impacts CFTRΔF508 folding efficiency and the identity of CFTRΔF508's correctable folding defects...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743624/ https://ncbi.nlm.nih.gov/pubmed/19625452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0929 |
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