Interaction of Asymmetric ABCC9-Encoded Nucleotide Binding Domains Determines K(ATP) Channel SUR2A Catalytic Activity

Nucleotide binding domains (NBDs) secure ATP-binding cassette (ABC) transporter function. Distinct from traditional ABC transporters, ABCC9-encoded sulfonylurea receptors (SUR2A) form, with Kir6.2 potassium channels, ATP-sensitive K(+) (K(ATP)) channel complexes. SUR2A contains ATPase activity harbo...

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Main Authors: Park, Sungjo, Lim, Bernard B. C., Perez-Terzic, Carmen, Mer, Georges, Terzic, Andre
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743405/
https://ncbi.nlm.nih.gov/pubmed/18311911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr7007847
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