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Role for SUR2A ED Domain in Allosteric Coupling within the K(ATP) Channel Complex
Allosteric regulation of heteromultimeric ATP-sensitive potassium (K(ATP)) channels is unique among protein systems as it implies transmission of ligand-induced structural adaptation at the regulatory SUR subunit, a member of ATP-binding cassette ABCC family, to the distinct pore-forming K(+) (Kir6....
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248718/ https://ncbi.nlm.nih.gov/pubmed/18299394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709852 |
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