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QUATERNARY STRUCTURE OF K(ATP) CHANNEL SUR2A NUCLEOTIDE BINDING DOMAINS RESOLVED BY SYNCHROTRON RADIATION X-RAY SCATTERING
Heterodimeric nucleotide binding domains NBD1/NBD2 distinguish the ATP-binding cassette protein SUR2A, a recognized regulatory subunit of cardiac ATP-sensitive K(+) (K(ATP)) channels. The tandem function of these core domains ensures metabolism-dependent gating of the Kir6.2 channel pore, yet their...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818519/ https://ncbi.nlm.nih.gov/pubmed/19919849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2009.11.005 |
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