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A Mechanism Linking Extra Centrosomes to Chromosomal Instability
Chromosome instability (CIN) is a hallmark of many tumors and correlates with the presence of extra centrosomes1-4. However, a direct mechanistic link between extra centrosomes and CIN has not been established. It has been proposed that extra centrosomes generate CIN by promoting multipolar anaphase...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743290/ https://ncbi.nlm.nih.gov/pubmed/19506557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08136 |
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