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Mps1 as a link between centrosomes and genomic instability

Centrosomes are microtubule-organizing centers that must be precisely duplicated prior to mitosis. Centrosomes regulate mitotic spindle assembly, and the presence of excess centrosomes leads to the production of aberrant mitotic spindles that generate chromosome segregation errors. Many human tumors...

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Detalhes bibliográficos
Main Authors: Kasbek, Christopher, Yang, Ching-Hui, Fisk, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760674/
https://ncbi.nlm.nih.gov/pubmed/19274768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20476
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