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Mps1 as a link between centrosomes and genomic instability
Centrosomes are microtubule-organizing centers that must be precisely duplicated prior to mitosis. Centrosomes regulate mitotic spindle assembly, and the presence of excess centrosomes leads to the production of aberrant mitotic spindles that generate chromosome segregation errors. Many human tumors...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760674/ https://ncbi.nlm.nih.gov/pubmed/19274768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20476 |
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