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Mps1 Phosphorylation Sites Regulate the Function of Centrin 2 in Centriole Assembly

The nondegradable Mps1(Δ12/13) protein drives centriole overproduction, suggesting that Mps1 phosphorylates a subset of centrosomal proteins to drive the assembly of new centrioles. Here we identify three Mps1 phosphorylation sites within the centriolar protein Centrin 2 (Cetn2). Although centrioles...

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Autors principals: Yang, Ching-Hui, Kasbek, Christopher, Majumder, Shubhra, Yusof, Adlina Mohd, Fisk, Harold A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002389/
https://ncbi.nlm.nih.gov/pubmed/20980622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-04-0298
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