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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
Multiple centrosomes in tumor cells create the potential for multipolar divisions that can lead to aneuploidy and cell death. Nevertheless, many cancer cells successfully divide because of mechanisms that suppress multipolar mitoses. A genome-wide RNAi screen in Drosophila S2 cells and a secondary a...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518815/ https://ncbi.nlm.nih.gov/pubmed/18662975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1700908 |
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