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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

Multiple centrosomes in tumor cells create the potential for multipolar divisions that can lead to aneuploidy and cell death. Nevertheless, many cancer cells successfully divide because of mechanisms that suppress multipolar mitoses. A genome-wide RNAi screen in Drosophila S2 cells and a secondary a...

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Bibliografische gegevens
Hoofdauteurs: Kwon, Mijung, Godinho, Susana A., Chandhok, Namrata S., Ganem, Neil J., Azioune, Ammar, Thery, Manuel, Pellman, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518815/
https://ncbi.nlm.nih.gov/pubmed/18662975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1700908
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