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Causes and consequences of centrosome abnormalities in cancer

Centrosome amplification is a hallmark of cancer. However, despite significant progress in recent years, we are still far from understanding how centrosome amplification affects tumorigenesis. Boveri's hypothesis formulated more than 100 years ago was that aneuploidy induced by centrosome ampli...

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Detalhes bibliográficos
Main Authors: Godinho, S. A., Pellman, D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113111/
https://ncbi.nlm.nih.gov/pubmed/25047621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0467
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