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Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE
BACKGROUND: UDP-GlcNAc 2-epimerase/ManNAc 6-kinase, GNE, is a bi-functional enzyme that plays a key role in sialic acid biosynthesis. Mutations of the GNE protein cause sialurea or autosomal recessive inclusion body myopathy/Nonaka myopathy. GNE is the only human protein that contains a kinase domai...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742894/ https://ncbi.nlm.nih.gov/pubmed/19841673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007165 |
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