Crystal Structures of the Tetratricopeptide Repeat Domains of Kinesin Light Chains: Insight into Cargo Recognition Mechanisms

Kinesin-1 transports various cargos along the axon by interacting with the cargos through its light chain subunit. Kinesin light chains (KLC) utilize its tetratricopeptide repeat (TPR) domain to interact with over 10 different cargos. Despite a high sequence identity between their TPR domains (87%),...

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Autores principales: Zhu, Haizhong, Lee, Han Youl, Tong, Yufeng, Hong, Bum-Soo, Kim, Kyung-Phil, Shen, Yang, Lim, Kyung Jik, Mackenzie, Farrell, Tempel, Wolfram, Park, Hee-Won
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314626/
https://ncbi.nlm.nih.gov/pubmed/22470497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033943
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