Crystal Structures of the Tetratricopeptide Repeat Domains of Kinesin Light Chains: Insight into Cargo Recognition Mechanisms

Kinesin-1 transports various cargos along the axon by interacting with the cargos through its light chain subunit. Kinesin light chains (KLC) utilize its tetratricopeptide repeat (TPR) domain to interact with over 10 different cargos. Despite a high sequence identity between their TPR domains (87%),...

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Detalhes bibliográficos
Main Authors: Zhu, Haizhong, Lee, Han Youl, Tong, Yufeng, Hong, Bum-Soo, Kim, Kyung-Phil, Shen, Yang, Lim, Kyung Jik, Mackenzie, Farrell, Tempel, Wolfram, Park, Hee-Won
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314626/
https://ncbi.nlm.nih.gov/pubmed/22470497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033943
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