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Cab45b, a Munc18b-interacting Partner, Regulates Exocytosis in Pancreatic β-Cells
Cab45b is a cytosolic Ca(2+)-binding protein reported to regulate zymogen secretion in pancreatic acini. We now show that Cab45b is also expressed in pancreatic islet β-cells and interacts there with the Sec1-Munc18 protein Munc18b. We employed patch clamp cell capacitance measurements to show that...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742849/ https://ncbi.nlm.nih.gov/pubmed/19487699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017467 |
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