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Mismatch Recognition Protein MutSβ Does Not Hijack (CAG)(n) Hairpin Repair in Vitro

CAG repeats form stable hairpin structures, which are believed to be responsible for CAG repeat expansions associated with certain human neurological diseases. Human cells possess an accurate DNA hairpin repair system that prevents expansion of disease-associated CAG repeats. Based on transgenic ani...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tian, Lei, Hou, Caixia, Tian, Keli, Holcomb, Nathaniel C., Gu, Liya, Li, Guo-Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742808/
https://ncbi.nlm.nih.gov/pubmed/19525234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.014977
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