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Retinoic acid prevents virus-induced airway hyperreactivity and M(2) receptor dysfunction via anti-inflammatory and antiviral effects

Inhibitory M(2) muscarinic receptors on airway parasympathetic nerves normally limit acetylcholine release. Viral infections decrease M(2) receptor function, increasing vagally mediated bronchoconstriction. Since retinoic acid deficiency causes M(2) receptor dysfunction, we tested whether retinoic a...

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Bibliografiske detaljer
Main Authors: Moreno-Vinasco, Liliana, Verbout, Norah G., Fryer, Allison D., Jacoby, David B.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742790/
https://ncbi.nlm.nih.gov/pubmed/19465517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90267.2008
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