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Interleukin-1β Mediates Virus-Induced M(2) Muscarinic Receptor Dysfunction and Airway Hyperreactivity

Respiratory viral infections are associated with the majority of asthma attacks. Inhibitory M(2) receptors on parasympathetic nerves, which normally limit acetylcholine (ACh) release, are dysfunctional after respiratory viral infection. Because IL-1β is up-regulated during respiratory viral infectio...

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Detalhes bibliográficos
Main Authors: Rynko, Abby E., Fryer, Allison D., Jacoby, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189486/
https://ncbi.nlm.nih.gov/pubmed/24735073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0009OC
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