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Retinoic acid prevents virus-induced airway hyperreactivity and M(2) receptor dysfunction via anti-inflammatory and antiviral effects

Inhibitory M(2) muscarinic receptors on airway parasympathetic nerves normally limit acetylcholine release. Viral infections decrease M(2) receptor function, increasing vagally mediated bronchoconstriction. Since retinoic acid deficiency causes M(2) receptor dysfunction, we tested whether retinoic a...

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Bibliografski detalji
Glavni autori: Moreno-Vinasco, Liliana, Verbout, Norah G., Fryer, Allison D., Jacoby, David B.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742790/
https://ncbi.nlm.nih.gov/pubmed/19465517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90267.2008
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