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Retinoic acid prevents virus-induced airway hyperreactivity and M(2) receptor dysfunction via anti-inflammatory and antiviral effects
Inhibitory M(2) muscarinic receptors on airway parasympathetic nerves normally limit acetylcholine release. Viral infections decrease M(2) receptor function, increasing vagally mediated bronchoconstriction. Since retinoic acid deficiency causes M(2) receptor dysfunction, we tested whether retinoic a...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742790/ https://ncbi.nlm.nih.gov/pubmed/19465517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90267.2008 |
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