Point Mutations in Membrane Proteins Reshape Energy Landscape and Populate Different Unfolding Pathways

Using single-molecule force spectroscopy, we investigated the effect of single point mutations on the energy landscape and unfolding pathways of the transmembrane protein bacteriorhodopsin. We show that the unfolding energy barriers in the energy landscape of the membrane protein followed a simple t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Sapra, K. Tanuj, Balasubramanian, G. Prakash, Labudde, Dirk, Bowie, James U., Muller, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742699/
https://ncbi.nlm.nih.gov/pubmed/18191146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.027
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge