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Mapping the energy landscape for second-stage folding of a single membrane protein

Membrane proteins are designed to fold and function in a lipid membrane, yet folding experiments within a native membrane environment are challenging to design. Here we show that single-molecule forced unfolding experiments can be adapted to study helical membrane protein folding under native-like b...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Min, Duyoung, Jefferson, Robert E, Bowie, James U, Yoon, Tae-Young
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986997/
https://ncbi.nlm.nih.gov/pubmed/26479439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1939
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