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Intestinal alkaline phosphatase regulates protective surface microclimate pH in rat duodenum
Regulation of localized extracellular pH (pH(o)) maintains normal organ function. An alkaline microclimate overlying the duodenal enterocyte brush border protects the mucosa from luminal acid. We hypothesized that intestinal alkaline phosphatase (IAP) regulates pH(o) due to pH-sensitive ATP hydrolys...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742288/ https://ncbi.nlm.nih.gov/pubmed/19451200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172270 |
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