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Intestinal alkaline phosphatase regulates protective surface microclimate pH in rat duodenum
Regulation of localized extracellular pH (pH(o)) maintains normal organ function. An alkaline microclimate overlying the duodenal enterocyte brush border protects the mucosa from luminal acid. We hypothesized that intestinal alkaline phosphatase (IAP) regulates pH(o) due to pH-sensitive ATP hydrolys...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742288/ https://ncbi.nlm.nih.gov/pubmed/19451200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172270 |
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