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Intestinal alkaline phosphatase regulates protective surface microclimate pH in rat duodenum

Regulation of localized extracellular pH (pH(o)) maintains normal organ function. An alkaline microclimate overlying the duodenal enterocyte brush border protects the mucosa from luminal acid. We hypothesized that intestinal alkaline phosphatase (IAP) regulates pH(o) due to pH-sensitive ATP hydrolys...

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Bibliografski detalji
Glavni autori: Mizumori, Misa, Ham, Maggie, Guth, Paul H, Engel, Eli, Kaunitz, Jonathan D, Akiba, Yasutada
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742288/
https://ncbi.nlm.nih.gov/pubmed/19451200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172270
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