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Peripheral sensitisation of nociceptors via G-proteindependent potentiation of mechanotransduction currents

Mechanical stimuli impinging on the skin are converted into electrical signals by mechanically gated ion channels located at the peripheral nerve endings of dorsal root ganglion (DRG) neurons. Under inflammatory conditions sensory neurons are commonly sensitised to mechanical stimuli; a putative mec...

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Bibliografske podrobnosti
Main Authors: Lechner, Stefan G, Lewin, Gary R
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742277/
https://ncbi.nlm.nih.gov/pubmed/19505980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.175059
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