Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

Although endocannabinoids constitute one of the first lines of defense against pain, the anatomical locus and the precise receptor mechanisms underlying cannabinergic modulation of pain are uncertain. Clinical exploitation of the system is severely hindered by the cognitive deficits, memory impairme...

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Autors principals: Agarwal, Nitin, Pacher, Pal, Tegeder, Irmgard, Amaya, Fumimasa, Constantin, Cristina E, Brenner, Gary J, Rubino, Tiziana, Michalski, Christoph W, Marsicano, Giovanni, Monory, Krisztina, Mackie, Ken, Marian, Claudiu, Batkai, Sandor, Parolaro, Daniela, Fischer, Michael J, Reeh, Peter, Kunos, George, Kress, Michaela, Lutz, Beat, Woolf, Clifford J, Kuner, Rohini
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234438/
https://ncbi.nlm.nih.gov/pubmed/17558404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1916
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