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Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

Although endocannabinoids constitute one of the first lines of defense against pain, the anatomical locus and the precise receptor mechanisms underlying cannabinergic modulation of pain are uncertain. Clinical exploitation of the system is severely hindered by the cognitive deficits, memory impairme...

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Detalhes bibliográficos
Main Authors: Agarwal, Nitin, Pacher, Pal, Tegeder, Irmgard, Amaya, Fumimasa, Constantin, Cristina E, Brenner, Gary J, Rubino, Tiziana, Michalski, Christoph W, Marsicano, Giovanni, Monory, Krisztina, Mackie, Ken, Marian, Claudiu, Batkai, Sandor, Parolaro, Daniela, Fischer, Michael J, Reeh, Peter, Kunos, George, Kress, Michaela, Lutz, Beat, Woolf, Clifford J, Kuner, Rohini
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234438/
https://ncbi.nlm.nih.gov/pubmed/17558404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1916
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