A Molecular Basis of Analgesic Tolerance to Cannabinoids

Clinical usage of cannabinoids in chronic pain states is limited by their central side effects and the pharmacodynamic tolerance that sets in after repeated dosage. Analgesic tolerance to cannabinoids in vivo could be caused by agonist-induced downregulation and intracellular trafficking of cannabin...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tappe-Theodor, Anke, Agarwal, Nitin, Katona, István, Rubino, Tiziana, Martini, Lene, Swiercz, Jakub, Mackie, Ken, Monyer, Hannah, Parolaro, Daniela, Whistler, Jennifer, Kuner, Thomas, Kuner, Rohini
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672554/
https://ncbi.nlm.nih.gov/pubmed/17428994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5648-06.2007
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