Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS

Lipid signaling pathways are involved in cell growth, differentiation, and apoptosis, and could have a role in the progression of myelodysplastic syndromes (MDS) into acute myeloid leukemia (AML). Indeed, recent studies showed that phosphoinositide-phospholipase (PI-PL)Cbeta1 mono-allelic deletion c...

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Bibliografiska uppgifter
Huvudupphovsmän: Follo, Matilde Y., Finelli, Carlo, Mongiorgi, Sara, Clissa, Cristina, Bosi, Costanza, Testoni, Nicoletta, Chiarini, Francesca, Ramazzotti, Giulia, Baccarani, Michele, Martelli, Alberto M., Manzoli, Lucia, Martinelli, Giovanni, Cocco, Lucio
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741479/
https://ncbi.nlm.nih.gov/pubmed/19805378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907109106
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