Lipoprotein accumulation in macrophages via TLR4-dependent fluid phase uptake

Toll-like receptor-4 (TLR4) recognizes microbial pathogens, such as lipopolysaccharide (LPS), and mediates LPS-induced proinflammatory cytokine secretion, as well as microbial uptake by macrophages. In addition to exogenous pathogens, TLR4 recognizes modified self, such as minimally oxidized low-den...

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Autori principali: Choi, Soo-Ho, Harkewicz, Richard, Lee, Jee Hyun, Boullier, Agnès, Almazan, Felicidad, Li, Andrew C., Witztum, Joseph L., Bae, Yun Soo, Miller, Yury I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741301/
https://ncbi.nlm.nih.gov/pubmed/19461045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.192880
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