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STIM1 and calmodulin interact with Orai1 to induce Ca(2+)-dependent inactivation of CRAC channels
Ca(2+)-dependent inactivation (CDI) is a key regulator and hallmark of the Ca(2+) release-activated Ca(2+) (CRAC) channel, a prototypic store-operated Ca(2+) channel. Although the roles of the endoplasmic reticulum Ca(2+) sensor STIM1 and the channel subunit Orai1 in CRAC channel activation are beco...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741279/ https://ncbi.nlm.nih.gov/pubmed/19706428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906781106 |
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