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Intact signal peptide of CD18, the β-subunit of β(2)-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin
Signal peptides of membrane proteins are cleaved by endoplasmic reticulum-resident signal peptidase, and thus, are not present on mature membrane proteins. Here, we report that, contrary to the paradigm, the signal peptide of ruminant CD18, the β-subunit of β(2)-integrins, is not cleaved. Intriguing...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741271/ https://ncbi.nlm.nih.gov/pubmed/19706410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906775106 |
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