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Monomeric Expression of Bovine β(2)-Integrin Subunits Reveals Their Role in Mannheimia haemolytica Leukotoxin-Induced Biological Effects

The ruminant-specific leukotoxin (Lkt) of Mannheimia haemolytica is the key virulence factor contributing to the pathogenesis of lung injury in bovine pneumonic pasteurellosis. Previous studies by us and others indicate that M. haemolytica Lkt binds to CD18, the β subunit of bovine β(2)-integrins on...

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Detalhes bibliográficos
Main Authors: Dassanayake, Rohana P., Maheswaran, Samuel K., Srikumaran, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044532/
https://ncbi.nlm.nih.gov/pubmed/17698568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00808-07
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