Bovine CD18 Is Necessary and Sufficient To Mediate Mannheimia (Pasteurella) haemolytica Leukotoxin-Induced Cytolysis

Leukotoxin (Lkt) secreted by Mannheimia (Pasteurella) haemolytica is an RTX toxin which is specific for ruminant leukocytes. Lkt binds to β(2) integrins on the surface of bovine leukocytes. β(2) integrins have a common β subunit, CD18, that associates with three distinct α chains, CD11a, CD11b, and...

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Detaylı Bibliyografya
Asıl Yazarlar: Deshpande, M. S., Ambagala, T. C., Ambagala, A. P. N., Kehrli, M. E., Srikumaran, S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC128227/
https://ncbi.nlm.nih.gov/pubmed/12183553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5058-5068.2002
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