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Precise gene editing paves the way for derivation of Mannheimia haemolytica leukotoxin-resistant cattle
Signal peptides of membrane proteins are cleaved by signal peptidase once the nascent proteins reach the endoplasmic reticulum. Previously, we reported that, contrary to the paradigm, the signal peptide of ruminant CD18, the β subunit of β(2) integrins, is not cleaved and hence remains intact on mat...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135351/ https://ncbi.nlm.nih.gov/pubmed/27799556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613428113 |
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