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pHLIP-mediated Translocation of Membrane Impermeable Molecules into Cells
Our goal is to define the properties of cell-impermeable cargo molecules that can be delivered into cells by pHLIP (pH (Low) Insertion Peptide), which can selectively target tumors in vivo based on their acidity. Using biophysical methods and fluorescence microscopy, we show that pHLIP can successfu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741147/ https://ncbi.nlm.nih.gov/pubmed/19635412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.06.006 |
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