Neutralizing a Surface Charge on the FMN Subdomain Increases the Activity of Neuronal Nitric-oxide Synthase by Enhancing the Oxygen Reactivity of the Enzyme Heme-Nitric Oxide Complex

Nitric-oxide synthases (NOSs) are calmodulin-dependent flavoheme enzymes that oxidize l-Arg to nitric oxide (NO) and l-citrulline. Their catalytic behaviors are complex and are determined by their rates of heme reduction (k(r)), ferric heme-NO dissociation (k(d)), and ferrous heme-NO oxidation (k(ox...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Haque, Mohammad Mahfuzul, Fadlalla, Mohammed, Wang, Zhi-Qiang, Ray, Sougata Sinha, Panda, Koustubh, Stuehr, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740548/
https://ncbi.nlm.nih.gov/pubmed/19473991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013144
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados