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Charge Pairing Interactions Control the Conformational Setpoint and Motions of the FMN Domain in Neuronal Nitric Oxide Synthase
The Nitric Oxide Synthases (NOS; EC 1.14.13.39) contain a C-terminal flavoprotein domain (NOSred) that binds FAD and FMN and an N-terminal oxygenase domain that binds heme. Evidence suggests that the FMN-binding domain undergoes large conformational motions to shuttle electrons between the NADPH/FAD...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882132/ https://ncbi.nlm.nih.gov/pubmed/23289611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121488 |
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