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Glycopeptide-preferring Polypeptide GalNAc Transferase 10 (ppGalNAc T10), Involved in Mucin-type O-Glycosylation, Has a Unique GalNAc-O-Ser/Thr-binding Site in Its Catalytic Domain Not Found in ppGalNAc T1 or T2

Mucin-type O-gly co sy la tion is initiated by a large family of UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferases (ppGalNAc Ts) that transfer GalNAc from UDP-GalNAc to the Ser and Thr residues of polypeptide acceptors. Some members of the family prefer previously gly co sylated peptides (...

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Detalhes bibliográficos
Main Authors: Perrine, Cynthia L., Ganguli, Anjali, Wu, Peng, Bertozzi, Carolyn R., Fritz, Timothy A., Raman, Jayalakshmi, Tabak, Lawrence A., Gerken, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740463/
https://ncbi.nlm.nih.gov/pubmed/19460755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017236
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