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Acetylation of the DNA Binding Domain Regulates Transcription-independent Apoptosis by p53

The tumor suppressor p53 induces apo pto sis by altering the transcription of pro-apo pto tic targets in the nucleus and by a direct, nontranscriptional role at the mitochondria. Although the post-translational modifications regulating nuclear apo pto tic functions of p53 have been thoroughly charac...

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Hlavní autoři: Sykes, Stephen M., Stanek, Timothy J., Frank, Amanda, Murphy, Maureen E., McMahon, Steven B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740446/
https://ncbi.nlm.nih.gov/pubmed/19494119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026096
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