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Acetylation of the DNA Binding Domain Regulates Transcription-independent Apoptosis by p53
The tumor suppressor p53 induces apo pto sis by altering the transcription of pro-apo pto tic targets in the nucleus and by a direct, nontranscriptional role at the mitochondria. Although the post-translational modifications regulating nuclear apo pto tic functions of p53 have been thoroughly charac...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740446/ https://ncbi.nlm.nih.gov/pubmed/19494119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026096 |
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