FoxO1 induces apoptosis in skeletal myotubes in a DNA-binding-dependent manner

Recent studies indicate that FoxO transcription factors play an important role in promoting muscle atrophy. To study mechanisms mediating effects of FoxO proteins on muscle wasting, FoxO1-estrogen receptor fusion proteins that are activated by treatment with 4-hydroxytamoxifen (4-OH-T) were stably t...

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Autori principali: McLoughlin, Thomas J., Smith, Sierra M., DeLong, Alissa D., Wang, Hengbing, Unterman, Terry G., Esser, Karyn A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
Soggetti:
Muscle Cell Biology and Cell Motility
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740395/
https://ncbi.nlm.nih.gov/pubmed/19553561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00502.2008
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