Transcriptional regulation of FoxO3 gene by glucocorticoids in murine myotubes

Glucocorticoids and FoxO3 exert similar metabolic effects in skeletal muscle. FoxO3 gene expression was increased by dexamethasone (Dex), a synthetic glucocorticoid, both in vitro and in vivo. In C2C12 myotubes the increased expression is due to, at least in part, the elevated rate of FoxO3 gene tra...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Kuo, Taiyi, Liu, Patty H., Chen, Tzu-Chieh, Lee, Rebecca A., New, Jenny, Zhang, Danyun, Lei, Cassandra, Chau, Andy, Tang, Yicheng, Cheung, Edna, Wang, Jen-Chywan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824139/
https://ncbi.nlm.nih.gov/pubmed/26758684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00214.2015
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