Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis

Glucocorticoids promote lipolysis in white adipose tissue (WAT) to adapt to energy demands under stress, whereas superfluous lipolysis causes metabolic disorders, including dyslipidemia and hepatic steatosis. Glucocorticoid-induced lipolysis requires the phosphorylation of cytosolic hormone-sensitiv...

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Gepubliceerd in:Diabetes
Hoofdauteurs: Kuo, Taiyi, Chen, Tzu-Chieh, Lee, Rebecca A., Nguyen, Nguyen Huynh Thao, Broughton, Augusta E., Zhang, Danyun, Wang, Jen-Chywan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2017
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440017/
https://ncbi.nlm.nih.gov/pubmed/28292967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0831
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