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Regulation of the substrate preference of p190RhoGAP by PKC–mediated phosphorylation of a phospholipid binding site

The Rho family GTPases are stringently regulated through the action of a large family of GTPase activating proteins (GAPs) that stimulate their relatively weak intrinsic GTP hydrolyzing activity. The p190RhoGAPs, which include the p190A and p190B proteins are potent and widely expressed GAPs acting...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lévay, Magdolna, Settleman, Jeffrey, Ligeti, Erzsébet
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739883/
https://ncbi.nlm.nih.gov/pubmed/19673492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900667y
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