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Regulation of the substrate preference of p190RhoGAP by PKC–mediated phosphorylation of a phospholipid binding site

The Rho family GTPases are stringently regulated through the action of a large family of GTPase activating proteins (GAPs) that stimulate their relatively weak intrinsic GTP hydrolyzing activity. The p190RhoGAPs, which include the p190A and p190B proteins are potent and widely expressed GAPs acting...

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Detalhes bibliográficos
Main Authors: Lévay, Magdolna, Settleman, Jeffrey, Ligeti, Erzsébet
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739883/
https://ncbi.nlm.nih.gov/pubmed/19673492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900667y
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