p190A RhoGAP Is a Glycogen Synthase Kinase-3-β Substrate Required for Polarized Cell Migration

The Rho GTPases are critical regulators of the actin cytoskeleton and are required for cell adhesion, migration, and polarity. Among the key Rho regulatory proteins in the context of cell migration are the p190 RhoGAPs (p190A and p190B), which function to modulate Rho signaling in response to integr...

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Bibliografiske detaljer
Main Authors: Jiang, Wei, Betson, Martha, Mulloy, Roseann, Foster, Rosemary, Lévay, Magdolna, Ligeti, Erzsébet, Settleman, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475707/
https://ncbi.nlm.nih.gov/pubmed/18502760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802588200
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