Nalaganje...

A 1,2-d(GpG) Cisplatin Intrastrand Cross-link Influences the Rotational and Translational Setting of DNA in Nucleosomes

The mechanism of action of platinum-based anticancer drugs such as cis-diamminedichloro-platinum( II), or cisplatin, involves three sequential steps: cell entry, drug activation, and target binding. A major target in the cell, responsible for the anticancer activity, is nuclear DNA, which is package...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ober, Matthias, Lippard, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739446/
https://ncbi.nlm.nih.gov/pubmed/18269283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja710220x
Oznake: Označite
Brez oznak, prvi označite!