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Statistical Use of Argonaute Expression and RISC Assembly in microRNA Target Identification
MicroRNAs (miRNAs) posttranscriptionally regulate targeted messenger RNAs (mRNAs) by inducing cleavage or otherwise repressing their translation. We address the problem of detecting m/miRNA targeting relationships in homo sapiens from microarray data by developing statistical models that are motivat...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739424/ https://ncbi.nlm.nih.gov/pubmed/19779550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000516 |
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