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The leukotriene E(4) puzzle: finding the missing pieces and revealing the pathobiologic implications
The intracellular parent of the cysteinyl leukotrienes (cys-LTs), leukotriene (LT) C(4), is formed by conjugation of LTA(4) and reduced glutathione by LTC(4) synthase in mast cells, eosinophils, basophils, and macrophages. After extracellular export, LTC(4) is converted to LTD(4) and LTE(4) by seque...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739263/ https://ncbi.nlm.nih.gov/pubmed/19647860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.05.046 |
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