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DIFERENTIALLY EXPRESSED ADENYLYL CYCLASE ISOFORMS MEDIATE SECRETORY FUNCTIONS IN CHOLANGIOCYTE SUBPOPULATION

cAMP is generated by adenylyl cyclases (ACs) a group of enzymes with different tissue specificity and regulation. We hypothesized that AC isoforms are heterogeneously expressed along the biliary tree, are associated with specific secretory stimuli and are differentially modulated in cholestasis. MET...

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Detalhes bibliográficos
Main Authors: Strazzabosco, Mario, Fiorotto, Romina, Melero, Saida, Glaser, Shannon, Francis, Heather, Spirlì, Carlo, Alpini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738985/
https://ncbi.nlm.nih.gov/pubmed/19444869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22926
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