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Post-Translational Regulation of Polycystin-2 Protein Expression as a Novel Mechanism of Cholangiocyte Reaction and Repair from Biliary Damage

Polycystin-2 (PC2 /TRPP2), a member of the transient receptor potential channels (TRP) family, is a non-selective calcium channel. Mutations in PC2/TRPP2 are associated with Polycystic Liver Diseases. PC2-defective cholangiocytes shows increased production of cAMP, PKA-dependent activation of the ER...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Spirli, Carlo, Villani, Ambra, Mariotti, Valeria, Fabris, Luca, Fiorotto, Romina, Strazzabosco, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681612/
https://ncbi.nlm.nih.gov/pubmed/26313562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28138
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