GABA induces thee differentiation of small into large cholangiocytes by activation of Ca(2+)/CaMK I-dependent adenylyl cyclase 8

Large but not small cholangiocytes: (i) secrete bicarbonate by interaction with secretin receptors (SR) through activation of cystic fibrosis transmembrane regulator (CFTR), chloride bicarbonate anion exchanger 2 (Cl(−)/HCO(3)(−) AE2) and adenylyl cyclase 8 (AC8) (proteins regulating large biliary f...

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Detalhes bibliográficos
Main Authors: Mancinelli, Romina, Franchitto, Antonio, Glaser, Shannon, Meng, Fanyin, Onori, Paolo, DeMorrow, Sharon, Francis, Heather, Venter, Julie, Carpino, Guido, Baker, Kimberley, Han, Yuyan, Ueno, Yoshiyuki, Gaudio, Eugenio, Alpini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733050/
https://ncbi.nlm.nih.gov/pubmed/23389926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26308
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