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The Liver-Brain Axis of Alcohol-Mediated Neurodegeneration: Role of Toxic Lipids

Alcohol abuse causes progressive toxicity and degeneration in liver and brain due to insulin resistance, which exacerbates oxidative stress and pro-inflammatory cytokine activation. Alcohol-induced steatohepatitis promotes synthesis and accumulation of ceramides and other toxic lipids that cause ins...

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Detalles Bibliográficos
Main Authors: de la Monte, Suzanne M., Longato, Lisa, Tong, Ming, DeNucci, Sarah, Wands, Jack R.
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738898/
https://ncbi.nlm.nih.gov/pubmed/19742171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph6072055
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